Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 9/20 | 0.56 |
| ▸ | HRH2 | P25021 | 8/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | PTAFR | P25105 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15103054 | 0.86 | KDM4E (0.55) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL17706209 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL9819864 | 0.81 | SIGMAR1 (0.69) | ALDH1A1SIGMAR1HTR2AOPRM1ADORA3 | |
| SCHEMBL6103099 | 0.78 | SIGMAR1 (0.48) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL5715475 | 0.78 | SIGMAR1 (0.46) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL5715116 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL6102814 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL5715419 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL5715230 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EALOX15SIGMAR1HTR2A | |
| SCHEMBL27492297 | 0.78 | CHRNA7 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144035-A | Chemical intermediates for platelet activating factor antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-4948795-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0350145-A2 | Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |