Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CCR3 | P51677 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508433 | 0.87 | HRH2 (0.63) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| Hydrochloric Acid SCHEMBL10509615 | 0.86 | HRH1 (0.61) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL9054221 | 0.85 | L3MBTL1 (0.64) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL27564818 | 0.83 | SIGMAR1 (0.76) | SIGMAR1MEN1KMT2ACCR3FAAH | |
| SCHEMBL27629467 | 0.83 | SIGMAR1 (0.56) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL30671736 | 0.82 | SIGMAR1 (0.70) | SIGMAR1HTR7CCR3FAAH | |
| SCHEMBL7475308 | 0.81 | ALDH1A1 (0.70) | L3MBTL1TSHRALDH1A1NPC1RAB9A | |
| SCHEMBL9634840 | 0.81 | SIGMAR1 (0.61) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL9744374 | 0.81 | ALDH1A1 (0.57) | SIGMAR1HTR2AOPRM1ADORA3HTR7 | |
| SCHEMBL4904424 | 0.81 | SIGMAR1 (0.57) | SIGMAR1HTR2AOPRM1ADORA3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |