Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744496 | 1.00 | PTGS2 (0.39) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL9744978 | 0.78 | PTGS2 (0.41) | PTGS2PTGS1HTR2AHTR2CHTR2B | |
| SCHEMBL9577632 | 0.77 | LMNA (0.39) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL9577636 | 0.77 | LMNA (0.39) | ALDH1A1LMNAHPGDHTTKMT2A | |
| SCHEMBL9744624 | 0.75 | HMGCR (0.54) | — | |
| SCHEMBL9745032 | 0.75 | HMGCR (0.54) | — | |
| SCHEMBL9745036 | 0.75 | HMGCR (0.54) | — | |
| SCHEMBL9749704 | 0.74 | PTGS2 (0.32) | PTGS2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9749709 | 0.74 | PTGS2 (0.32) | PTGS2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL9845315 | 0.73 | MAPT (0.35) | PTGS2PTGS1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114964-A | Aryl-substituted benzocycloalkyl-derived anti-atherosclerotic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | disclosed |