Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 3/20 | 0.36 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 7/20 | 0.31 |
| ▸ | CES1 | P23141 | 5/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325177 | 0.85 | ALDH1A1 (0.39) | TACR3ALDH1A1 | |
| SCHEMBL9744772 | 0.83 | TACR3 (0.37) | EPHX1TACR3FAAH | |
| SCHEMBL9328354 | 0.83 | TACR3 (0.37) | TACR3 | |
| SCHEMBL9767101 | 0.78 | FAAH (0.37) | ALDH1A1FAAHCES1CES2MEN1 | |
| SCHEMBL7326578 | 0.77 | ALDH1A1 (0.38) | TACR3ALDH1A1 | |
| SCHEMBL9326410 | 0.76 | CA2 (0.32) | — | |
| SCHEMBL7303995 | 0.74 | CA2 (0.40) | ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL7301168 | 0.74 | CA2 (0.40) | ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL9671527 | 0.74 | CA2 (0.40) | ALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL9671129 | 0.74 | CA2 (0.40) | ALDH1A1MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322953-A | Antiinflammatory agents; intermediates for 2-furanone compounds | ALLERGAN, INC. (US) | 1994-06-21 | — | — | US | disclosed |
| US-5298633-A | Silane intermediates | ALLERGAN, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| US-5171863-A | 2-trialkylsily-4-substituted furan derivatives | ALLERGAN, INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5082954-A | Intermediates and processes for preparing 4-substituted 2-5(H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |