Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210555 | 0.90 | THRA (0.60) | TDP1MAPTMAPK1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL28760001 | 0.89 | THRA (0.59) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL10659256 | 0.89 | CA12 (0.71) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL27937324 | 0.88 | MAPT (0.54) | TDP1MAPTMAPK1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5280503 | 0.87 | CA12 (0.69) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL4761104 | 0.87 | THRA (0.57) | TDP1MAPTMAPK1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL27337480 | 0.86 | MAPT (0.52) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL7441999 | 0.86 | ALDH1A1 (0.62) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL7796598 | 0.86 | CA12 (0.49) | TDP1MAPTMAPK1KMT2AKDM4E | |
| SCHEMBL16404276 | 0.86 | CA12 (0.49) | TDP1MAPTMAPK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205068-B1 | LYSERGIC-ACID AMIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-01-02 | — | — | EP | claimed |