Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28760001 | 0.98 | THRA (0.59) | THRATHRBL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL9744775 | 0.90 | TDP1 (0.62) | L3MBTL1HPGDSMN1; SMN2CA12CA1 | |
| SCHEMBL4761104 | 0.89 | THRA (0.57) | THRATHRBL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL27937324 | 0.87 | MAPT (0.54) | L3MBTL1HPGDSMN1; SMN2CA12CA1 | |
| Hydrochloric Acid SCHEMBL27337480 | 0.85 | MAPT (0.52) | L3MBTL1HPGDSMN1; SMN2CA12CA1 | |
| Hydrochloric Acid SCHEMBL11664928 | 0.85 | THRA (0.61) | THRATHRBL3MBTL1MAPTTDP1 | |
| SCHEMBL5023251 | 0.84 | HPGD (0.50) | THRATHRBL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL11137757 | 0.83 | HPGD (0.54) | L3MBTL1HPGDSMN1; SMN2MAPTKMT2A | |
| Benzoic Acid SCHEMBL4086034 | 0.82 | TSHR (0.58) | HPGDSMN1; SMN2CA12CA9MAPT | |
| Butyrophenone SCHEMBL11798375 | 0.82 | L3MBTL1 (0.59) | L3MBTL1HPGDSMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689929-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2024-05-31 | — | — | CN | disclosed |
| CN-114401935-B | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2024-04-05 | — | — | CN | disclosed |
| EP-3816164-B1 | ISOTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND AS IRAK4 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2024-04-03 | — | — | EP | disclosed |
| US-20230331739-A1 | INDOLO HEPTAMYL OXIME ANALOG CRYSTAL AS PARP INHIBITOR AND METHOD FOR PREPARING SAME | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
| EP-4190790-A1 | INDOLO HEPTAMYL OXIME ANALOG CRYSTAL AS PARP INHIBITOR AND METHOD FOR PREPARING SAME | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2023-06-07 | — | — | EP | disclosed |
| CN-113365998-B | Indolo hepta-acyloxime analogs for PARP inhibitors | 正大天晴药业集团股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115698019-A | Crystal of indolo-hepta-acyloxime analogue used as PARP inhibitor and preparation method thereof | 正大天晴药业集团股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111205286-B | Nitrile methyl piperazine derivative as KRAS G12C mutant protein inhibitor and application thereof | 中科苏州药物研究院 | 2022-12-13 | — | — | CN | disclosed |
| CN-109384778-B | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 赛克里翁治疗有限公司 | 2022-12-13 | — | — | CN | disclosed |
| CN-112442030-B | Pyridinopyrimidine derivatives as KRASG12C mutant protein inhibitors | 南京明德新药研发有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-20040104377-A1 | Non-toxic corrosion-protection pigments based on rare earth elements | UNIVERSITY OF DAYTON | 2004-06-03 | — | — | US | disclosed |
| US-20040020568-A1 | Non-toxic corrosion-protection conversion coats based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-02-05 | — | — | US | disclosed |
| US-20040016910-A1 | Non-toxic corrosion-protection rinses and seals based on rare earth elements | DAYTON, UNIVERSITY OF | 2004-01-29 | — | — | US | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| CN-1298867-A | Process for preparing alpha-amidophenylketone with optical activity | AIKE PHARMACEUTICAL SCIENCE AN (CN) | 2001-06-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331739-A1 | INDOLO HEPTAMYL OXIME ANALOG CRYSTAL AS PARP INHIBITOR AND METHOD FOR PREPARING SAME | PARP1, PARP2, PARP8 | THRA 4068/4885THRB 3676/4885L3MBTL1 4070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.