Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744904 | 1.00 | NAAA (0.36) | NAAAMEN1MAPTKMT2AATM | |
| SCHEMBL6686977 | 0.76 | POLB (0.36) | MEN1MAPTKMT2AATMLMNA | |
| SCHEMBL19806301 | 0.75 | — | — | |
| SCHEMBL22708176 | 0.73 | MAPT (0.33) | NAAAMEN1MAPTKMT2AATM | |
| SCHEMBL25436787 | 0.73 | PLA2G1B (0.34) | NAAAFAAH | |
| SCHEMBL6956924 | 0.71 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL16586003 | 0.69 | IDH1 (0.44) | NAAAIDH1 | |
| SCHEMBL2073646 | 0.69 | IDH1 (0.44) | NAAAIDH1 | |
| SCHEMBL7306476 | 0.69 | NAAA (0.47) | NAAAIDH1FAAH | |
| SCHEMBL3773685 | 0.67 | LMNA (0.47) | NAAAMEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091575-A | Renin inhibitor | ABBOTT LABORATORIES (US) | 1992-02-25 | — | — | US | disclosed |