Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 12/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289208 | 0.95 | ELANE (0.47) | ELANENPC1RAB9ACMA1 | |
| SCHEMBL7276163 | 0.90 | ELANE (0.39) | ELANENPC1RAB9A | |
| SCHEMBL7288778 | 0.87 | ELANE (0.34) | ELANENPC1RAB9A | |
| SCHEMBL7288148 | 0.86 | KMT2A (0.40) | ELANENPC1RAB9ACMA1KMT2A | |
| SCHEMBL7285218 | 0.81 | ELANE (0.40) | ELANENPC1RAB9ACMA1KMT2A | |
| SCHEMBL7276968 | 0.81 | ELANE (0.46) | ELANENPC1RAB9ACMA1KMT2A | |
| SCHEMBL7285860 | 0.80 | NPC1 (0.39) | ELANENPC1RAB9AKMT2A | |
| SCHEMBL7286288 | 0.80 | FAAH (0.39) | ELANE | |
| SCHEMBL7286039 | 0.79 | ELANE (0.52) | ELANENPC1RAB9ACMA1KMT2A | |
| SCHEMBL7004719 | 0.79 | NPC1 (0.37) | ELANENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164371-A | HETEROCYCLIC KETONES | ICI AMERICAS INC. (US) | 1992-11-17 | — | — | US | disclosed |