Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837941 | 0.75 | MGAM (0.42) | CYP2D6CYP2C9CYP2C19CA12CA1 | |
| SCHEMBL9744937 | 0.73 | MAPT (0.33) | CYP2D6CYP2C9CYP2C19PPARDTSHR | |
| SCHEMBL4623923 | 0.70 | MGAM (0.38) | CYP2D6CA12CA1CA2CA9 | |
| SCHEMBL9744920 | 0.69 | CYP2D6 (0.43) | CYP2D6CYP2C9CYP2C19PPARDTSHR | |
| SCHEMBL9653714 | 0.69 | GLO1 (0.40) | CYP2D6CYP2C9CYP2C19PPARDTSHR | |
| SCHEMBL5873561 | 0.69 | GLO1 (0.40) | CYP2D6CYP2C9CYP2C19PPARDTSHR | |
| SCHEMBL28462097 | 0.69 | TSHR (0.39) | PPARDTSHR | |
| SCHEMBL8576108 | 0.69 | GLO1 (0.40) | CYP2D6CYP2C9CYP2C19PPARDTSHR | |
| SCHEMBL2458072 | 0.68 | TSHR (0.48) | PPARDTSHR | |
| SCHEMBL28069497 | 0.67 | TSHR (0.43) | PPARDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175344-A | Anticonvulsants, anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0233154-B1 | UNSATURATED AMINO-ACIDS | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| US-5051413-A | For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0233154-A2 | Unsaturated amino-acids | CIBA-GEIGY AG (CH) | 1987-08-19 | — | — | EP | disclosed |