Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325309 | 0.94 | LMNA (0.42) | LMNAMAPTMAPK1ELANEALDH1A1 | |
| SCHEMBL9745062 | 0.90 | PPARG (0.39) | LMNAMAPTMAPK1ELANE | |
| SCHEMBL9746538 | 0.90 | LMNA (0.36) | LMNAMAPTMAPK1ELANEALDH1A1 | |
| SCHEMBL9327442 | 0.85 | FAAH (0.39) | FAAHPRKCA | |
| SCHEMBL9128899 | 0.85 | LMNA (0.38) | LMNAMAPTMAPK1ELANEALDH1A1 | |
| SCHEMBL9670950 | 0.84 | GLS2 (0.35) | ALDH1A1FAAHPRKCA | |
| SCHEMBL9671037 | 0.84 | GLS2 (0.35) | ALDH1A1FAAHPRKCA | |
| SCHEMBL9325034 | 0.84 | GLS2 (0.35) | ALDH1A1FAAHPRKCA | |
| SCHEMBL7295059 | 0.84 | GLS2 (0.35) | ALDH1A1FAAHPRKCA | |
| SCHEMBL9669998 | 0.83 | TLR2 (0.39) | FAAHPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |