Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975323 | 0.93 | HSD11B1 (0.77) | HSD11B1HSD11B2 | |
| SCHEMBL16208111 | 0.89 | HSD11B1 (0.59) | HSD11B1HSD11B2 | |
| SCHEMBL975644 | 0.88 | HSD11B1 (0.85) | HSD11B1HSD11B2 | |
| SCHEMBL973704 | 0.86 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL972585 | 0.86 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL10297230 | 0.86 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL973126 | 0.86 | HSD11B1 (0.72) | HSD11B1HSD11B2 | |
| SCHEMBL973486 | 0.82 | HSD11B1 (0.75) | HSD11B1HSD11B2 | |
| SCHEMBL16208193 | 0.82 | HSD11B1 (0.61) | HSD11B1HSD11B2 | |
| SCHEMBL975033 | 0.81 | HSD11B1 (0.84) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009391-A1 | TETRAHYDROQUINOXALINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | US | claimed |
| US-20110009391-A1 | TETRAHYDROQUINOXALINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009391-A1 | TETRAHYDROQUINOXALINE UREA DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | BHMT, UGDH, NNMT | HSD11B1 4293/4885HSD11B2 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.