Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951403 | 0.82 | TYR (0.44) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL10431546 | 0.82 | ADRA2C (0.43) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL25911995 | 0.78 | ADRA2C (0.40) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL25909654 | 0.78 | ADRA2C (0.40) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL6420857 | 0.76 | TAAR1 (0.42) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL25799302 | 0.76 | TAAR1 (0.42) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL7795647 | 0.74 | TSHR (0.43) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL7769306 | 0.74 | TSHR (0.43) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL208902 | 0.74 | TSHR (0.43) | ADRA2CKDM4ELMNAADRA2AHIF1A | |
| SCHEMBL22283420 | 0.74 | ALDH1A1 (0.43) | ADRA2CKDM4ELMNAADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099006-A | ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates | RHONE-POULENC INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0242855-A2 | Crosslinking reaction inhibitor for collagen | LION CORPORATION (JP) | 1987-10-28 | — | — | EP | disclosed |