Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.37 |
| ▸ | PDCD4 | Q53EL6 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326904 | 0.93 | LMNA (0.42) | PRKCAPDCD4LMNAMAPTMAPK1 | |
| SCHEMBL8985047 | 0.90 | PRKCA (0.40) | PRKCAPDCD4LMNAPTPN1 | |
| SCHEMBL8985099 | 0.89 | FFAR4 (0.38) | PRKCAPDCD4LMNAMAPK1PTPN1 | |
| SCHEMBL9282825 | 0.89 | PPARG (0.39) | PRKCAPDCD4LMNACNR1CNR2 | |
| SCHEMBL9327053 | 0.84 | PTPN1 (0.43) | PRKCAPTPN1 | |
| SCHEMBL8985076 | 0.83 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL14339054 | 0.83 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL7294590 | 0.83 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9671381 | 0.83 | PDCD4 (0.47) | PDCD4 | |
| SCHEMBL9327478 | 0.83 | PTPN1 (0.42) | PRKCAMAPTPTPN1DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |