Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607285 | 0.81 | CA2 (0.50) | TDP1CA2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10299307 | 0.80 | KMT2A (0.46) | TDP1CA2MEN1KMT2ACYP1A2 | |
| SCHEMBL30363574 | 0.78 | MEN1 (0.51) | TDP1CA2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL776996 | 0.78 | IDO1 (0.48) | CA2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8637781 | 0.77 | CA2 (0.43) | CA2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL21645319 | 0.77 | IDO1 (0.56) | TDP1CA2FFAR1AKR1B1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28355658 | 0.77 | IDO1 (0.47) | CA2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5679281 | 0.77 | CA2 (0.45) | TDP1CA2FFAR1MEN1KMT2A | |
| SCHEMBL28509699 | 0.77 | CA2 (0.49) | CA2FFAR1KMT2ANPC1RAB9A | |
| SCHEMBL5676950 | 0.77 | IDO1 (0.47) | CA2NPC1RAB9ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171909-B1 | SPIRO-OXAZINE COMPOUNDS AND PREPARATION THEREOF AND PHOTOCHROMIC SHAPED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4784474-A | LENSES; WINDOWS | TORAY INDUSTRIES, INC. (JP) | 1988-11-15 | — | — | US | disclosed |
| EP-0171909-A1 | Spiro-oxazine compounds and preparation thereof and photochromic shaped article | TORAY INDUSTRIES, INC. (JP) | 1986-02-19 | — | — | EP | disclosed |