Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745651 | 0.80 | TDP1 (0.45) | KMT2AMEN1CA2CYP1A2CYP2D6 | |
| SCHEMBL901166 | 0.73 | KMT2A (0.50) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL20597973 | 0.72 | KMT2A (0.48) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2939781 | 0.71 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL9815022 | 0.71 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2939780 | 0.71 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8927201 | 0.70 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL278717 | 0.70 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL67895 | 0.70 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL67894 | 0.70 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169176-B2 | Pyrene compound and organic electroluminescent device including the same | CANON KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20120168736-A1 | NOVEL PYRENE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120168736-A1 | NOVEL PYRENE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | CYP1A1, PAH, CYP2E1 | KMT2A 3318/4885MEN1 1818/4885CA2 3346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.