Dimethylamine

Dimethylamine

SCHEMBL1361903

CNC.N#Cc1cccc(Oc2ccccc2)c1C#N

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.43
MAPK14 Q16539 1/20 0.42
RAF1 P04049 2/20 0.40
MAP2K1 Q02750 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
HSD11B1 P28845 1/20 0.40
ALDH1A1 P00352 3/20 0.40
AR P10275 2/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669346 0.93 SMN1; SMN2 (0.57) POLBGAASMN1; SMN2KDM4EMAPT
Ammonia Solution, Strong SCHEMBL28193306 0.92 SMN1; SMN2 (0.56) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL9745478 0.90 SMN1; SMN2 (0.58) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL9746326 0.90 SMN1; SMN2 (0.54) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL9745662 0.90 SMN1; SMN2 (0.58) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL9746110 0.87 SMN1; SMN2 (0.52) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL9746273 0.86 SMN1; SMN2 (0.54) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL21352429 0.83 SMN1; SMN2 (0.50) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL8975487 0.82 POLB (0.73) POLBGAASMN1; SMN2KDM4EMAPT
SCHEMBL17090701 0.81 MAPT (0.47) POLBGAASMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8242262-B2 Process for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA'DI ESERCIZIO S.P.A. (IT) 2012-08-14 US disclosed
US-8067404-B2 Phthalocyanine derivatives, process for their preparation, pharmaceutical compositions containing them and their use L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA'DI ESERCIZIO S.P.A. (IT) 2011-11-29 US disclosed
EP-1883640-B1 PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP MOLTENI & C (IT) 2009-08-26 EP disclosed
US-20090131393-A1 Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) 2009-05-21 US disclosed
US-20090131392-A1 PHTALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) 2009-05-21 US disclosed
EP-1883641-B1 PHTHALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE MOLTENI & C (IT) 2008-11-26 EP disclosed
EP-1883640-A2 PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI (IT) 2008-02-06 EP disclosed
EP-1883641-A1 PHTHALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A (IT) 2008-02-06 EP disclosed
WO-2006117399-A1 PHTHALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE L. MOLTENI & C. DEI FRATELLI ALITTI - SOCIETA' DI ESERCIZIO S.P.A. (IT) 2006-11-09 WO disclosed
WO-2006117396-A2 PROCESS FOR PREPARING CHLORIDES OF PHTHALOCYANINE DERIVATIVES COMPRISING AT LEAST A QUATERNARY AMMONIUM GROUP L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A. (IT) 2006-11-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131392-A1 PHTALOCYANINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE PHLPP1, PHLPP2, PHYKPL POLB 988/4885GAA 616/4885SMN1; SMN2 3753/4885
US-20090131393-A1 Process for Preparing Chlorides of Phthalocyanine Derivatives Comprising at Least a Quaternary Ammonium Group PHLPP1, PHPT1, PHLPP2 POLB 1188/4885GAA 693/4885SMN1; SMN2 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.