Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | WNT3A | P56704 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758861 | 0.84 | CES2 (0.69) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL31557727 | 0.83 | CES2 (0.62) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL31557717 | 0.82 | CES2 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL744906 | 0.82 | CTNNB1 (0.62) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL28415441 | 0.82 | CES2 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL25348845 | 0.82 | CES2 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL9468405 | 0.82 | ALDH1A1 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL4508253 | 0.82 | CES2 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL2096246 | 0.82 | CES2 (0.61) | CES2CTNNB1WNT3AALDH1A1POLB | |
| SCHEMBL31016229 | 0.81 | CES2 (0.65) | CES2CTNNB1WNT3AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108930-A | Deprotenization of biological sample, reacting it with pyridine aldehyde to form pyridine aldehyde-substituted hydrazone of corresponding aminoguanidine; isolation, chromatographic analysis for quantity | ALTEON INC. (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0448228-A2 | Aminoguanidine assay and applications thereof | ALTEON INC. (US) | 1991-09-25 | — | — | EP | disclosed |