SCHEMBL97458

SCHEMBL97458

NC(=O)/C=C\C(=O)Nc1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.63
▸ MAPT P10636 6/20 0.63
▸ HTT P42858 2/20 0.63
▸ DDAH1 O94760 1/20 0.63
▸ THRB P10828 2/20 0.50
▸ CA12 O43570 4/20 0.47
▸ CA1 P00915 4/20 0.47
▸ CA2 P00918 4/20 0.47
▸ CA9 Q16790 4/20 0.47
▸ POLB P06746 2/20 0.47
▸ LPAR2 Q9HBW0 1/20 0.46
▸ LPAR3 Q9UBY5 1/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ LMNA P02545 2/20 0.46
▸ PKM P14618 1/20 0.46
▸ TIMP3 P35625 1/20 0.45
▸ TGM2 P21980 1/20 0.45
▸ KDM4E B2RXH2 3/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2016893 1.00 ALDH1A1 (0.63) ALDH1A1MAPTHTTDDAH1THRB
SCHEMBL5481885 0.87 MAPT (0.63) ALDH1A1MAPTHTTDDAH1CA12
SCHEMBL1827416 0.87 MAPT (0.63) ALDH1A1MAPTHTTDDAH1CA12
SCHEMBL2429556 0.86 ALDH1A1 (0.81) ALDH1A1MAPTHTTDDAH1THRB
SCHEMBL2016896 0.85 ALDH1A1 (0.67) ALDH1A1MAPTTHRBPOLBLPAR2
SCHEMBL10799923 0.85 MAPT (0.49) ALDH1A1MAPTTHRBCA12CA1
SCHEMBL2016892 0.85 ALDH1A1 (0.67) ALDH1A1MAPTTHRBPOLBLPAR2
SCHEMBL8673997 0.85 ALDH1A1 (0.67) ALDH1A1MAPTTHRBPOLBLPAR2
SCHEMBL10799929 0.85 MAPT (0.49) ALDH1A1MAPTTHRBCA12CA1
SCHEMBL28201181 0.81 TGM2 (0.53) ALDH1A1MAPTDDAH1THRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611752-B1 DISPERSANT FOR GYPSUM PLASTER COMPOSITIONS SIKA TECH AG (CH) 2017-04-26 — — EP disclosed
EP-2321233-B1 DISPERSING AGENTS FOR GYPSUM PLASTER COMPOSITIONS SIKA TECH AG (CH) 2017-03-22 — — EP disclosed
EP-2611752-A1 DISPERSANT FOR GYPSUM PLASTER COMPOSITIONS Sika Technology AG (CH) 2013-07-10 — — EP disclosed
US-8362117-B2 Method for stabilizing polycarboxylates SIKA TECHNOLOGY AG (CH) 2013-01-29 — — US disclosed
EP-2161247-B1 Method for stabilising polycarboxylates SIKA TECHNOLOGY AG (CH) 2012-10-24 — — EP disclosed
US-8273814-B2 Emulsifying polymers and their use SIKA TECHNOLOGY AG (CH) 2012-09-25 — — US disclosed
US-8273808-B2 Dispersing agents for gypsum plaster compositions SIKA TECHNOLOGY AG (CH) 2012-09-25 — — US disclosed
WO-2012028668-A1 DISPERSANT FOR GYPSUM PLASTER COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2012-03-08 — — WO disclosed
EP-2426095-A1 Dispersing agent for gipsum composition Sika Technology AG (CH) 2012-03-07 — — EP disclosed
US-20110213054-A1 METHOD FOR STABILIZING POLYCARBOXYLATES SIKA TECHNOLOGY AG (CH) 2011-09-01 — — US disclosed
US-20110160351-A1 DISPERSING AGENTS FOR GYPSUM PLASTER COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-06-30 — — US disclosed
EP-2321233-A1 DISPERSING AGENTS FOR GYPSUM PLASTER COMPOSITIONS Sika Technology AG (CH) 2011-05-18 — — EP disclosed
US-20100197840-A1 EMULSIFYING POLYMERS AND THEIR USE SIKA TECHNOLOGY AG (CH) 2010-08-05 — — US disclosed
EP-2176307-A1 EMULSIFYING POLYMERS AND THEIR USE Sika Technology AG (CH) 2010-04-21 — — EP disclosed
WO-2010026226-A1 METHOD FOR STABILIZING POLYCARBOXYLATES SIKA TECHNOLOGY AG (CH) 2010-03-11 — — WO disclosed
EP-2161247-A1 Method for stabilising polycarboxylates Sika Technology AG (CH) 2010-03-10 — — EP disclosed
EP-2154118-A1 Dispersing agent for gypsum compounds Sika Technology AG (CH) 2010-02-17 — — EP disclosed
WO-2010012804-A1 DISPERSING AGENTS FOR GYPSUM PLASTER COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2010-02-04 — — WO disclosed
WO-2009016213-A1 EMULSIFYING POLYMERS AND THEIR USE SIKA TECHNOLOGY AG (CH) 2009-02-05 — — WO disclosed
EP-2020422-A1 Emulgating polymers and their use Sika Technology AG (CH) 2009-02-04 — — EP disclosed
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