⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743530 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL9745832 | 0.75 | — | — | |
| SCHEMBL31380092 | 0.73 | TSHR (0.47) | — | |
| SCHEMBL29061729 | 0.73 | TSHR (0.47) | — | |
| SCHEMBL14562728 | 0.72 | GPR84 (0.37) | — | |
| SCHEMBL3841843 | 0.72 | CES1 (0.39) | — | |
| SCHEMBL9359877 | 0.71 | ABCC4 (0.48) | — | |
| SCHEMBL16872402 | 0.70 | CAMK2A (0.36) | — | |
| SCHEMBL344380 | 0.69 | TSHR (0.58) | — | |
| Acetic Acid SCHEMBL27955148 | 0.68 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | disclosed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0215817-A1 | CONTINUOUS-WEAR LENSES. | BAUSCH & LOMB (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0209597-A1 | EXTENDED-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1987-01-28 | — | — | EP | disclosed |
| WO-1986004341-A1 | CONTINUOUS-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| WO-1986004343-A1 | EXTENDED-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |