Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745825 | 0.83 | — | — | |
| SCHEMBL2368040 | 0.79 | — | — | |
| SCHEMBL7924271 | 0.74 | TSHR (0.48) | ALDH1A1 | |
| SCHEMBL2368028 | 0.73 | TGFBR1 (0.31) | — | |
| SCHEMBL18210535 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27553829 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL28116522 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL21811809 | 0.71 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL689956 | 0.71 | CES2 (0.46) | ALDH1A1 | |
| SCHEMBL12095005 | 0.71 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | disclosed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0209597-A1 | EXTENDED-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1987-01-28 | — | — | EP | disclosed |
| WO-1986004343-A1 | EXTENDED-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |