Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NGFR | P08138 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741078 | 0.86 | ALOX15 (0.50) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL9745897 | 0.81 | KDM4E (0.41) | BLMKDM4ETDP1MEN1KMT2A | |
| SCHEMBL9744469 | 0.81 | BLM (0.41) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| Potassium Ion SCHEMBL9741462 | 0.78 | PLA2G7 (0.31) | — | |
| SCHEMBL9740597 | 0.70 | BLM (0.45) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL9741107 | 0.69 | GPR35 (0.45) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL9741440 | 0.69 | BLM (0.44) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL436330 | 0.67 | NFKB1 (0.50) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL11883433 | 0.66 | GPR35 (0.61) | BLMALOX15NFKB1SMN1; SMN2KDM4E | |
| SCHEMBL19349224 | 0.65 | GPR35 (0.41) | GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |