Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746867 | 0.89 | VEGFA (0.47) | SMN1; SMN2KDM4ESLC6A4ALDH1A1POLB | |
| SCHEMBL9746326 | 0.89 | SMN1; SMN2 (0.54) | SCN9ASMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL669346 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EALDH1A1POLBGAA | |
| SCHEMBL9746042 | 0.85 | SMN1; SMN2 (0.43) | SCN9ASMN1; SMN2KDM4ESLC6A4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28193306 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EALDH1A1POLBGAA | |
| SCHEMBL9747114 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALDH1A1POLBGAA | |
| SCHEMBL9746284 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4ESLC6A4ALDH1A1POLB | |
| SCHEMBL9746110 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EALDH1A1POLBGAA | |
| SCHEMBL9745662 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1POLBGAA | |
| SCHEMBL9745478 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |