Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744817 | 0.83 | HDAC3 (0.38) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6529111 | 0.80 | GPR119 (0.46) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL2937645 | 0.79 | GPR119 (0.47) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL28319882 | 0.75 | HDAC6 (0.37) | HDAC1HDAC2L3MBTL1 | |
| SCHEMBL7957605 | 0.71 | KCNA5 (0.33) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL1019092 | 0.71 | CA1 (0.50) | GPR119PPARGPPARAEPHX2ADRB2 | |
| SCHEMBL7640149 | 0.70 | LMNA (0.38) | HDAC3HDAC1HDAC2NCOR2EPHX2 | |
| SCHEMBL9003727 | 0.70 | PPARG (0.39) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL9983224 | 0.70 | CA14 (0.32) | HDAC1HDAC2GRM2 | |
| SCHEMBL1309204 | 0.70 | CA14 (0.41) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098996-A | Fluorination of compounds for use in diagnosis of nuclear medicine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-03-24 | — | — | US | disclosed |