Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937645 | 0.83 | GPR119 (0.47) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5737167 | 0.83 | MAPT (0.42) | HDAC3HDAC1HDAC2NCOR2SMN1; SMN2 | |
| SCHEMBL4514786 | 0.81 | ALDH1A1 (0.43) | HDAC3HDAC1HDAC2NCOR2HPGD | |
| SCHEMBL9746186 | 0.80 | GPR119 (0.43) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1019092 | 0.75 | CA1 (0.50) | GPR119PPARGPPARAEPHX2ADRB2 | |
| SCHEMBL29067296 | 0.74 | GPR119 (0.45) | GPR119HPGDSMN1; SMN2 | |
| SCHEMBL7531272 | 0.73 | PAX8 (0.50) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1935308 | 0.73 | PPARG (0.46) | GPR119HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL3745549 | 0.73 | HDAC3 (0.60) | HDAC3HDAC1HDAC2NCOR2PPARG | |
| SCHEMBL3376998 | 0.72 | NOS1 (0.47) | GPR119PPARGPPARAPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601384-A1 | METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS | Amersham Health AS (NO) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004080492-A1 | METHODS OF RADIOFLUORINATION OF BIOLOGICALLY ACTIVE VECTORS | AMERSHAM HEALTH AS (NO) | 2004-09-23 | — | — | WO | disclosed |