Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SI | P14410 | 3/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272875 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL563078 | 0.78 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL29845601 | 0.77 | KCNMA1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL890612 | 0.77 | KCNMA1 (0.67) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL13772814 | 0.77 | KCNMA1 (0.57) | SMN1; SMN2RAB9AALDH1A1KCNMA1TSHR | |
| SCHEMBL11222166 | 0.76 | POLB (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL20156571 | 0.75 | GAA (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL29475382 | 0.74 | KCNMA1 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1KCNMA1 | |
| SCHEMBL24222175 | 0.74 | KCNMA1 (0.50) | SMN1; SMN2RAB9AALDH1A1KCNMA1TSHR | |
| SCHEMBL25873809 | 0.74 | KCNMA1 (0.50) | SMN1; SMN2RAB9AALDH1A1KCNMA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141990-A | Protected phenyl benzotriazole uv rad absorber | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-08-25 | — | — | US | disclosed |