Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4706646 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL9747159 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL9747450 | 0.79 | — | — | |
| SCHEMBL1513386 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL14413661 | 0.76 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL15144934 | 0.75 | HMGCR (0.31) | ALDH1A1TSHR | |
| SCHEMBL126072 | 0.74 | — | — | |
| SCHEMBL10386061 | 0.74 | ALOX15 (0.54) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL10386492 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TSHRLMNAHSD17B10ALOX15 | |
| SCHEMBL18446 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |