SCHEMBL9746559

SCHEMBL9746559

Clc1ccc(Cc2cc(Cl)ccc2Sc2ccc(Cl)cc2Cc2ccc(Cl)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
HIF1A Q16665 4/20 0.46
CYP3A4 P08684 3/20 0.46
HPGD P15428 3/20 0.46
ALOX15 P16050 3/20 0.46
MAPT P10636 2/20 0.46
HSD17B10 Q99714 2/20 0.46
SLC6A4 P31645 2/20 0.43
HSP90AA1 P07900 2/20 0.41
HTT P42858 2/20 0.41
IDO1 P14902 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
SLC22A1 O15245 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPA5 P11021 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11487325 0.85 MAPT (0.45) MEN1KMT2AMAPTSLC6A4IDO1
SCHEMBL3196242 0.77 SLC6A4 (0.46) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL4440726 0.75 SLC6A4 (0.66) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL6299244 0.73 SLC6A4 (0.44) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL9746564 0.73 MEN1 (0.47) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL11722438 0.72 IDO1 (0.56) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL2154366 0.72 ITGB2 (0.47) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL11758917 0.71 MEN1 (0.50) MEN1KMT2ACYP3A4HPGDMAPT
SCHEMBL28685342 0.71 PTGDR (0.46) MEN1KMT2AHIF1ACYP3A4HPGD
SCHEMBL1106684 0.69 IDO1 (0.58) MEN1KMT2ACYP3A4MAPTSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0214507-B1 OUTDOOR FILMS STABILIZED AGAINST CHEMICAL ATTACK AMERICAN CYANAMID COMPANY (US) 1992-01-15 EP disclosed
EP-0214507-A2 Outdoor films stabilized against chemical attack AMERICAN CYANAMID COMPANY (US) 1987-03-18 EP disclosed
US-4434165-A Fungicidal compositions HOFFMANN-LA ROCHE INC. (US) 1984-02-28 US disclosed
US-4241058-A INSECTICIDES, MITICIDES, SYSTEMIC HOFFMANN-LA ROCHE INC. (US) 1980-12-23 US disclosed
US-4220663-A Combating pests with benzyl phenyl ethers BAYER AKTIENGESELLSCHAFT (DE) 1980-09-02 US disclosed
US-4202894-A AGRICULTURE HOFFMANN-LA ROCHE INC. (US) 1980-05-13 US disclosed
US-4174445-A INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-11-13 US disclosed
US-4174393-A INSECTICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1979-11-13 US disclosed
US-4172146-A Substituted phenyl derivatives CIBA-GEIGY CORPORATION (US) 1979-10-23 US disclosed
US-4153604-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1979-05-08 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3941829-A PESTICIDE CIBA-GEIGY CORPORATION (US) 1976-03-02 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed
US-3935224-A 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3933945-A O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932632-A Insecticidal compositions containing an organophosphorus compound and a thiolcarbamate BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed