Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299244 | 0.82 | SLC6A4 (0.44) | ITGB2ICAM1ITGALSLC6A4SLC6A2 | |
| SCHEMBL1399191 | 0.80 | HTR2A (0.55) | TAAR1HTR2ATRPM8MEN1CYP3A4 | |
| SCHEMBL1399414 | 0.78 | HTR2A (0.55) | HTR2ASLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL1399281 | 0.77 | HTR2A (0.58) | HTR2ATRPM8SLC6A4IDO1MAPT | |
| SCHEMBL1399308 | 0.77 | HTR2A (0.58) | HTR2ATRPM8IDO1MAPT | |
| SCHEMBL1399286 | 0.77 | MPO (0.58) | HTR2ATRPM8SLC6A4KMT2AIDO1 | |
| SCHEMBL4634057 | 0.77 | HTR2A (0.58) | HTR2ATRPM8SLC6A4KMT2AIDO1 | |
| SCHEMBL3196242 | 0.77 | SLC6A4 (0.46) | ITGB2ICAM1ITGALSLC6A4SLC6A2 | |
| SCHEMBL1570195 | 0.77 | TAAR1 (0.52) | TAAR1HTR2ATRPM8MEN1HSP90AA1 | |
| SCHEMBL30496773 | 0.77 | TAAR1 (0.56) | TAAR1HTR2ATRPM8MAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-12-04 | — | — | US | disclosed |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-9732106-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2017-08-15 | — | — | US | disclosed |
| EP-3184171-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2519532-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20160168180-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2016-06-16 | — | — | US | disclosed |
| US-9283555-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2016-03-15 | — | — | US | disclosed |
| US-20140221645-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-08-07 | — | — | US | disclosed |
| US-8680003-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-03-25 | — | — | US | disclosed |
| EP-1904509-A2 | DIIMINE METAL COMPLEXES, SYNTHESIS, AND USE IN OLIGOMERIZATION AND POLYMERIZATION | Chevron Phillips Chemical Company (US) | 2008-04-02 | — | — | EP | disclosed |
| US-20080004459-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-01-03 | — | — | US | disclosed |
| US-20080004441-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2008-01-03 | — | — | US | disclosed |
| US-7271121-B2 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2007-09-18 | — | — | US | disclosed |
| US-7268096-B2 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2007-09-11 | — | — | US | disclosed |
| US-20070112150-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2007-05-17 | — | — | US | disclosed |
| WO-2007013931-A2 | DIIMINE METAL COMPLEXES, SYNTHESIS, AND USE IN OLIGOMERIZATION AND POLYMERIZATION | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2007-02-01 | — | — | WO | disclosed |
| US-20070027334-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2007-02-01 | — | — | US | disclosed |
| US-20070021608-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2007-01-25 | — | — | US | disclosed |
| US-7129304-B1 | Dimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2006-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027334-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | PICALM, AP1M1, AP2M1 | ITGB2 2180/4885ICAM1 954/4885ITGAL 1813/4885 |
| US-20080004441-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | PICALM, AP1M1, AP3M1 | ITGB2 2570/4885ICAM1 804/4885ITGAL 2141/4885 |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | NIT2, NCLN, NPM1 | ITGB2 3908/4885ICAM1 4656/4885ITGAL 3375/4885 |
| US-20070021608-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | PICALM, AP1M1, AP3M1 | ITGB2 2570/4885ICAM1 804/4885ITGAL 2141/4885 |
| US-20160168180-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ITGB2 3908/4885ICAM1 4656/4885ITGAL 3375/4885 |
| US-20140221645-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ITGB2 3908/4885ICAM1 4656/4885ITGAL 3375/4885 |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | ITGB2 3908/4885ICAM1 4656/4885ITGAL 3375/4885 |
| US-20080004459-A1 | Diimine metal complexes, methods of synthesis, and methods of using in oligomerization and polymerization | PICALM, AP1M1, AP2M1 | ITGB2 2301/4885ICAM1 958/4885ITGAL 1856/4885 |
| US-20070112150-A1 | Diimine metal complexes, methods of synthesis, and method of using in oligomerization and polymerization | PICALM, SPR, AP2M1 | ITGB2 2917/4885ICAM1 1655/4885ITGAL 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.