Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 4/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746746 | 0.80 | PDCD4 (0.37) | PDCD4FASNNAAACYP3A4 | |
| SCHEMBL9326304 | 0.75 | PRKCD (0.39) | PDCD4CYP3A4CYP2C19 | |
| SCHEMBL10576575 | 0.74 | ACHE (0.39) | PDCD4CYP2C9CYP2C19 | |
| SCHEMBL10577585 | 0.74 | ACHE (0.39) | PDCD4CYP2C9CYP2C19 | |
| SCHEMBL7298216 | 0.74 | ACHE (0.39) | PDCD4CYP2C9CYP2C19 | |
| SCHEMBL10576887 | 0.74 | ACHE (0.39) | PDCD4CYP2C9CYP2C19 | |
| SCHEMBL8985173 | 0.74 | CA1 (0.42) | PDCD4NAAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9128562 | 0.73 | ALDH1A1 (0.47) | NAAA | |
| SCHEMBL28007283 | 0.73 | EPHX1 (0.43) | NAAANOD1 | |
| SCHEMBL8985033 | 0.72 | DGKA (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081147-A | 4-(1-hydroxy-2-substituted amino)ethyl-5-hydroxy-2(5H)-furanones as anti-inflammatory agents | ALLERGAN, INC. (US) | 1992-01-14 | — | — | US | disclosed |