Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476006 | 0.87 | LMNA (0.49) | LMNAPOLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10538389 | 0.76 | TSHR (0.47) | LMNAPOLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8832657 | 0.74 | POLB (0.46) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL5167501 | 0.74 | POLB (0.46) | LMNAPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL246371 | 0.73 | — | — | |
| SCHEMBL12245645 | 0.73 | — | — | |
| SCHEMBL12362576 | 0.73 | — | — | |
| SCHEMBL5167062 | 0.72 | LMNA (0.47) | LMNAPOLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1149579 | 0.71 | — | — | |
| SCHEMBL41483 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204526-B1 | SILICONE ELASTOMERS | XEROX CORPORATION (US) | 1992-06-10 | — | — | EP | disclosed |
| EP-0204526-A2 | Silicone elastomers | XEROX CORPORATION (US) | 1986-12-10 | — | — | EP | disclosed |