Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878613 | 0.88 | HSD17B10 (0.52) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3371673 | 0.84 | HSD17B10 (0.55) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL27782235 | 0.83 | KDM4E (0.47) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL8879633 | 0.83 | KCNJ11 (0.39) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3369592 | 0.82 | HPGD (0.53) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3369494 | 0.82 | HSD17B10 (0.53) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3370877 | 0.82 | HPGD (0.53) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL2080934 | 0.81 | ALDH1A1 (0.43) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL19195723 | 0.78 | GLRA3 (0.66) | HSD17B10HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9325873 | 0.77 | GLRA3 (0.64) | HSD17B10HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648196-A | Water-soluble photoinitiators | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-07-15 | — | — | US | claimed |
| EP-2157143-B1 | NONAQUEOUS INKJET INK COMPOSITION | DAINIPPON TORYO KK (JP) | 2017-03-08 | — | — | EP | disclosed |
| EP-2284226-B1 | NONAQUEOUS INKJET INK COMPOSITION | DAINIPPON TORYO KK (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-9217053-B2 | Active ester resin, thermosetting resin composition, cured product of same, semiconductor encapsulation material, prepreg, circuit board, and build-up film | DIC CORPORATION (JP) | 2015-12-22 | — | — | US | disclosed |
| US-20150118499-A1 | ACTIVE ESTER RESIN, THERMOSETTING RESIN COMPOSITION, CURED PRODUCT OF SAME, SEMICONDUCTOR ENCAPSULATION MATERIAL, PREPREG, CIRCUIT BOARD, AND BUILD-UP FILM | DIC CORPORATION (JP) | 2015-04-30 | — | — | US | disclosed |
| US-8440745-B2 | Nonaqueous inkjet ink composition | DAI NIPPON TORYO CO., LTD. (JP) | 2013-05-14 | — | — | US | disclosed |
| CN-102958892-A | Method for preparing chemical compounds of interest by aromatic nucleophilic substitution | CENTRE NAT RECH SCIENT | 2013-03-06 | — | — | CN | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-8278371-B2 | Non-aqueous ink jet ink composition | DAI NIPPON TORYO CO., LTD. (JP) | 2012-10-02 | — | — | US | disclosed |
| EP-2157143-A1 | NONAQUEOUS INKJET INK COMPOSITION | Dai Nippon Toryo Co., Ltd. (JP) | 2010-02-24 | — | — | EP | disclosed |
| US-7601475-B2 | Carrier and developing agent for electrophotography | SHARP KABUSHIKI KAISHA (JP) | 2009-10-13 | — | — | US | disclosed |
| US-7572566-B2 | humidity resistance, small particle size, less likely to aggregate; for electrophotography; without causing thermal decomposition of a resin or separation of a release agent; applying shear stress to a mixture of a pigmented resin, an organic solvent, a polymer dispersant | SHARP KABUSHIKI KAISHA (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20080014514-A1 | Developer, developing device, image forming apparatus, and image forming method | SHARP KABUSHIKI KAISHA (JP) | 2008-01-17 | — | — | US | disclosed |
| US-20070059629-A1 | Carrier and developing agent for electrophotography | SHARP KABUSHIKI KAISHA (JP) | 2007-03-15 | — | — | US | disclosed |
| US-20070042283-A1 | Toner for development and method of producing toner | SHARP KABUSHIKI KAISHA (JP) | 2007-02-22 | — | — | US | disclosed |
| US-20070020550-A1 | Toner for electrostatic image development and process for preparing the same | SHARP KABUSHIKI KAISHA (JP) | 2007-01-25 | — | — | US | disclosed |
| US-20060222992-A1 | Toner for electrostatic image development and process for preparing the same | SHARP KABUSHIKI KAISHA (JP) | 2006-10-05 | — | — | US | disclosed |
| US-6013413-A | Alicyclic nortricyclene polymers and co-polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5648196-A | Water-soluble photoinitiators | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | COMT, NAA15, NUDC | HSD17B10 4089/4885HPGD 3538/4885MEN1 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.