Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 6/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3368588 | 0.85 | ALDH1A1 (0.53) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10587314 | 0.84 | KDM4E (0.46) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3371673 | 0.84 | HSD17B10 (0.55) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7653548 | 0.83 | KDM4E (0.47) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7650892 | 0.82 | KDM4E (0.46) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3369592 | 0.82 | HPGD (0.53) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3369494 | 0.82 | HSD17B10 (0.53) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL974719 | 0.82 | HSD17B10 (0.53) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7653270 | 0.81 | KDM4E (0.45) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7655987 | 0.81 | KDM4E (0.45) | HPGDKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6383274-B1 | Ink jet ink compositions and printing processes | XEROX CORPORATION | 2002-05-07 | — | — | US | claimed |
| CN-110035993-A | SUBSTITUTED PYRROLIDINES AS CFTR MODULATORS | 艾伯维公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-103443099-B | Regulate composition and the method for FXR | NOVARTIS AG (CH) | 2016-03-23 | — | — | CN | disclosed |
| US-8669375-B2 | Process for producing ester compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-11 | — | — | US | disclosed |
| CN-103443099-A | Compositions and methods for modulating FXR | IRM LLC | 2013-12-11 | — | — | CN | disclosed |
| CN-103370315-A | Compositions and methods for modulating farnesoid x receptors | IRM LLC | 2013-10-23 | — | — | CN | disclosed |
| US-20130066070-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-8318964-B2 | Process for producing ester compound | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20100324314-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-7833691-B2 | Heterocycle-bearing onium salts | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1443042-A1 | HYBRID ONIUM SALT | Wako Pure Chemical Industries, Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |
| US-6383274-B1 | Ink jet ink compositions and printing processes | XEROX CORPORATION | 2002-05-07 | — | — | US | disclosed |
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |
| EP-0307519-B1 | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0307519-A1 | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1989-03-22 | — | — | EP | disclosed |
| US-4814482-A | Trifluoromethylation process | ETHYL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4814480-A | Trifluoromethylation process | ETHYL CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4808748-A | Trifluoromethylation process | ETHYL CORPORATION (US) | 1989-02-28 | — | — | US | disclosed |
| US-4324681-A | Chiral supports for resolution of racemates | UOP INC. (US) | 1982-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130066070-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | ADH1C, ADH5, ADH1A | HPGD 2165/4885KDM4E 1421/4885MEN1 1733/4885 |
| US-20100324314-A1 | PROCESS FOR PRODUCING ESTER COMPOUND | ADH1C, ADH5, ADH1A | HPGD 1953/4885KDM4E 2044/4885MEN1 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.