SCHEMBL2080934

SCHEMBL2080934

CC(C)(C)c1ccc2ccccc2c1C(=O)OO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 2/20 0.43
NCEH1 Q6PIU2 2/20 0.41
KCNJ11 Q14654 6/20 0.38
ABCC9 O60706 3/20 0.38
ABCC8 Q09428 3/20 0.38
KCNJ8 Q15842 3/20 0.38
HPGD P15428 3/20 0.38
GAA P10253 2/20 0.37
PGR P06401 1/20 0.37
PTGS1 P23219 1/20 0.37
MAPK1 P28482 1/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
CYP2C19 P33261 1/20 0.37
MAPT P10636 2/20 0.36
POLB P06746 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974719 0.81 HSD17B10 (0.53) ALDH1A1HSD17B10KDM4EKCNJ11ABCC9
SCHEMBL8879633 0.79 KCNJ11 (0.39) ALDH1A1HSD17B10KDM4ENCEH1KCNJ11
SCHEMBL10530790 0.76 WDR5 (0.47) ALDH1A1HSD17B10KDM4ENCEH1HPGD
SCHEMBL12910945 0.73 ALDH1A1 (0.61) ALDH1A1HSD17B10KDM4ENCEH1HPGD
SCHEMBL28809073 0.73 NCEH1 (0.54) ALDH1A1KDM4ENCEH1KCNJ11ABCC9
SCHEMBL8526770 0.72 KCNJ11 (0.42) ALDH1A1HSD17B10KDM4ENCEH1KCNJ11
SCHEMBL13301636 0.72 CDC25B (0.48) ALDH1A1KDM4EHPGDGAAMAPK1
SCHEMBL363479 0.71 MAPT (0.41) ALDH1A1KDM4EGAAKMT2AMAPT
SCHEMBL4124570 0.71 HSD17B10 (0.46) ALDH1A1HSD17B10KDM4EKCNJ11ABCC9
SCHEMBL8526776 0.71 HSD17B10 (0.43) ALDH1A1HSD17B10KDM4ENCEH1KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4940648-A PEROXIDE OR PERESTER, 9-PHENYLACRIDINE OR PHENAZINE PHOTOINITIATOR HOECHST CELANESE CORPORATION (US) 1990-07-10 US claimed
US-9574116-B2 Adhesive propylene polymer composition suitable for extrusion coating of paper substrates Borealis, AG (AT) 2017-02-21 US disclosed
US-9431172-B2 Biaxially oriented electrical insulating film BOREALIS TECHNOLOGY OY (FI) 2016-08-30 US disclosed
CN-104073190-B Acrylic polymers adhesive composition suitable in extrusion coating paper substrates 北欧化工股份公司 2016-06-29 CN disclosed
US-9353296-B2 Adhesive propylene polymer composition suitable for extrusion coating of paper substrates BOREALIS AG (AT) 2016-05-31 US disclosed
CN-104152081-B Be applicable to the acrylic polymers adhesive composition of extrusion coating paper substrates BOREALIS AG (AT) 2016-05-18 CN disclosed
US-20160009959-A9 Adhesive Propylene Polymer Composition Suitable for Extrusion Coating of Paper Substrates BOREALIS AG (AT) 2016-01-14 US disclosed
US-20150064487-A1 Adhesive Propylene Polymer Composition Suitable for Extrusion Coating of Paper Substrates BOREALIS AG (AT) 2015-03-05 US disclosed
US-20150065640-A1 Adhesive Propylene Polymer Composition Suitable for Extrusion Coating of Paper Substrates BOREALIS AG (AT) 2015-03-05 US disclosed
US-8163845-B2 Biaxially oriented electrical insulating film TREOFAN GERMANY GMBH & CO. KG (DE) 2012-04-24 US disclosed
EP-0878567-A2 Polyolefin fibres and polyolefin yarns and textile materials thereof PCD Polymere AG (AT) 1998-11-18 EP disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed
US-5599652-A PHOTOPOLYMERIZABLE MIXTURES ALSO WITH FREE RADICAL POLYMERIZABLE COMPOUNDS AND PHOTOSENSITIZERS IMATION CORP. (US) 1997-02-04 US disclosed
EP-0733649-A1 Peroxycarboxylic ester initiators derived from nitrogen heterocycles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-25 EP disclosed
US-5527921-A USEFUL IN PHOTOPOLYMERIZABLE COMPOSITIONS AND PHOTOSENSITIVE ELEMENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-18 US disclosed
EP-0328036-B1 Photopolymerizable composition HOECHST CELANESE CORP (US) 1994-03-30 EP disclosed
US-4940648-A PEROXIDE OR PERESTER, 9-PHENYLACRIDINE OR PHENAZINE PHOTOINITIATOR HOECHST CELANESE CORPORATION (US) 1990-07-10 US disclosed
EP-0328036-A2 Photopolymerizable composition HOECHST CELANESE CORPORATION (US) 1989-08-16 EP disclosed