Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730000 | 0.86 | KDM4E (0.63) | SIRT6HTR1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL19926115 | 0.86 | HTR1A (0.58) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL9436570 | 0.86 | HTR1A (0.58) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL3187195 | 0.84 | SIRT6 (0.59) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL5187796 | 0.83 | SIRT6 (0.60) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL6945690 | 0.83 | SIRT6 (0.65) | SIRT6HTR1AMAPTLMNASMN1; SMN2 | |
| SCHEMBL5743368 | 0.83 | HTR1A (0.61) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL9436609 | 0.82 | HTR1A (0.61) | SIRT6HTR1AMAPTLMNAMAPK1 | |
| SCHEMBL5209234 | 0.82 | MAPT (0.67) | SIRT6HTR1AMAPTLMNAPOLB | |
| SCHEMBL12431530 | 0.81 | MAPT (0.70) | SIRT6HTR1AMAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474713-A1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS. | BASF AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015087-A1 | (METH)ACRYLATE COPOLYMERIZATES AND THEIR USE IN NON-LINEAR OPTICS AND IN THE PRODUCTION OF LANGMUIR-BLODGETT COATINGS | BASF AKTIENGESELLSCHAFT (DE) | 1990-12-13 | — | — | WO | disclosed |