Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266778 | 0.90 | TSHR (0.41) | CES1HTTMAPK1ALDH1A1MLYCD | |
| SCHEMBL10717585 | 0.87 | CES1 (0.47) | CES1HTTMAPK1MLYCDLMNA | |
| SCHEMBL32665929 | 0.87 | CES1 (0.47) | CES1HTTMAPK1MLYCDLMNA | |
| SCHEMBL10341072 | 0.87 | LIPG (0.50) | ALDH1A1MLYCDLMNA | |
| SCHEMBL9637940 | 0.87 | LIPG (0.50) | ALDH1A1MLYCDLMNA | |
| SCHEMBL9624253 | 0.87 | LIPG (0.50) | ALDH1A1MLYCDLMNA | |
| SCHEMBL19564481 | 0.84 | HCRTR1 (0.45) | HTTFOLH1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL9750554 | 0.82 | HCRTR1 (0.45) | HTTFOLH1HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL8957447 | 0.79 | HPGD (0.47) | CES1HTTFOLH1MAPK1ALDH1A1 | |
| SCHEMBL9045795 | 0.79 | HTT (0.37) | CES1HTTFOLH1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |