Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946327 | 0.87 | LCK (0.54) | ALDH1A1MAPTHPGDL3MBTL1POLB | |
| SCHEMBL9748700 | 0.81 | MAPT (0.50) | ALDH1A1MAPTHPGDLMNAL3MBTL1 | |
| SCHEMBL28755555 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDLMNAPOLB | |
| SCHEMBL31364601 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDLMNAL3MBTL1 | |
| SCHEMBL28215734 | 0.79 | HNF4A (0.56) | ALDH1A1MAPTLMNAL3MBTL1POLB | |
| SCHEMBL6120739 | 0.78 | POLB (0.49) | ALDH1A1MAPTLMNAL3MBTL1POLB | |
| SCHEMBL7736295 | 0.78 | NCEH1 (0.53) | ALDH1A1MAPTHPGDLMNAL3MBTL1 | |
| SCHEMBL11809956 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDLMNAL3MBTL1 | |
| SCHEMBL11078616 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDLMNAL3MBTL1 | |
| SCHEMBL30825381 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |