Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747321 | 0.81 | ALDH1A1 (0.49) | MAPTALDH1A1HPGDMAPK1POLB | |
| SCHEMBL8691455 | 0.78 | TDP1 (0.52) | ALDH1A1ESR1ESR2CYP3A4TSHR | |
| Acetic Acid SCHEMBL8609982 | 0.76 | TSHR (0.57) | MAPTALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL6121655 | 0.75 | CYP3A4 (0.44) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL18829453 | 0.75 | CYP3A4 (0.44) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL263311 | 0.74 | LMNA (0.72) | MAPTALDH1A1MAPK1POLBL3MBTL1 | |
| SCHEMBL29793639 | 0.74 | LMNA (0.72) | MAPTALDH1A1MAPK1POLBL3MBTL1 | |
| SCHEMBL12170111 | 0.73 | MEN1 (0.48) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL9747000 | 0.73 | CA2 (0.49) | MAPTALDH1A1POLBLMNAMEN1 | |
| SCHEMBL29642531 | 0.73 | MAPT (0.56) | MAPTALDH1A1HPGDMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |