Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748588 | 0.95 | KDM4E (0.66) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL8443211 | 0.95 | KDM4E (0.66) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL9387187 | 0.94 | KDM4E (0.69) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL27524922 | 0.89 | BCHE (0.63) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL9748781 | 0.88 | KDM4E (0.68) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL8474173 | 0.84 | BCHE (0.66) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL9384234 | 0.83 | KDM4E (0.72) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL9382159 | 0.83 | KDM4E (0.65) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL8523769 | 0.83 | KDM4E (0.62) | KDM4EGAAHTTBCHEACHE | |
| SCHEMBL9232310 | 0.82 | KDM4E (0.64) | KDM4EGAAHTTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |