Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 4/20 | 0.59 |
| ▸ | ACHE | P22303 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.57 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443211 | 1.00 | KDM4E (0.66) | KDM4EGAAALDH1A1HPGDBCHE | |
| SCHEMBL9747358 | 0.95 | KDM4E (0.63) | KDM4EGAAALDH1A1HPGDBCHE | |
| SCHEMBL9387187 | 0.92 | KDM4E (0.69) | KDM4EGAAALDH1A1BCHEACHE | |
| SCHEMBL27524922 | 0.87 | BCHE (0.63) | KDM4EGAABCHEACHEHTT | |
| SCHEMBL9748781 | 0.86 | KDM4E (0.68) | KDM4EGAAALDH1A1BCHEACHE | |
| SCHEMBL8474173 | 0.82 | BCHE (0.66) | KDM4EGAABCHEACHEHTT | |
| SCHEMBL9384234 | 0.81 | KDM4E (0.72) | KDM4EGAAALDH1A1BCHEACHE | |
| SCHEMBL9382159 | 0.81 | KDM4E (0.65) | KDM4EGAAALDH1A1BCHEACHE | |
| SCHEMBL8523769 | 0.81 | KDM4E (0.62) | KDM4EGAAALDH1A1BCHEACHE | |
| SCHEMBL9232310 | 0.81 | KDM4E (0.64) | KDM4EGAAALDH1A1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |