Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746625 | 0.91 | TSHR (0.41) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL4229900 | 0.88 | NAAA (0.47) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL9747319 | 0.84 | FAAH (0.39) | TSHRNAAAEPHX1PTPN7HMGCR | |
| SCHEMBL8163468 | 0.83 | ALDH1A1 (0.48) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL9747585 | 0.81 | FAAH (0.35) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL2529455 | 0.80 | NAAA (0.59) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL2946409 | 0.80 | NAAA (0.59) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL2530636 | 0.80 | NAAA (0.59) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL2945479 | 0.80 | NAAA (0.59) | TSHRNAAAEPHX1CA12CA1 | |
| SCHEMBL2530487 | 0.80 | NAAA (0.59) | TSHRNAAAEPHX1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204285-B1 | IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4725601-A | Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0204285-A1 | Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-10 | — | — | EP | disclosed |