Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747279 | 0.89 | MAPT (0.49) | LMNAMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL9747366 | 0.85 | BRD4 (0.40) | MAPTMEN1ALDH1A1HPGDALOX15 | |
| SCHEMBL9747703 | 0.80 | ALDH1A1 (0.41) | MAPTMEN1ALDH1A1HPGDALOX15 | |
| SCHEMBL3683241 | 0.78 | MAPT (0.45) | MAPTMEN1ALDH1A1HPGDALOX15 | |
| SCHEMBL9747505 | 0.78 | MAPT (0.48) | LMNAMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL31236067 | 0.77 | TAS2R14 (0.61) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8415280 | 0.77 | TAS2R14 (0.61) | MAPTMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9747794 | 0.77 | GRIN2D (0.45) | LMNAMAPTMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3683097 | 0.77 | MAPT (0.44) | MAPTMEN1ALDH1A1HPGDALOX15 | |
| SCHEMBL12848788 | 0.74 | GRIA1 (0.60) | LMNAMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |