Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.70 |
| ▸ | HRH1 | P35367 | 1/20 | 0.70 |
| ▸ | DRD3 | P35462 | 1/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8420827 | 0.98 | CHRM1 (0.67) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL924106 | 0.94 | CHRM1 (0.67) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL10640567 | 0.92 | CHRM1 (0.64) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3508609 | 0.90 | CHRM1 (0.61) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL1370161 | 0.89 | CPB2 (0.74) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL24199997 | 0.88 | GRIK1 (0.62) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6412189 | 0.88 | GRIK1 (0.62) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2228988 | 0.86 | CHRM1 (0.76) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL11880433 | 0.86 | CHRM1 (0.84) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8536227 | 0.86 | CPB2 (0.71) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443365-A | Method for determination of the valproic acid and reagents therein | DAINIPPON PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-04-17 | — | — | US | claimed |
| EP-0043285-B1 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1984-01-04 | — | — | EP | claimed |
| EP-0043285-A1 | Method for determination of valproic acid and reagents therein | Dainippon Pharmaceutical Co., Ltd. (JP) | 1982-01-06 | — | — | EP | claimed |
| CN-114646698-B | Method for detecting sodium valproate and related substances thereof in sodium valproate injection | 西安远大德天药业股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20220096639-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | Frequency Therapeutics, Inc. | 2022-03-31 | — | — | US | disclosed |
| EP-3921309-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| US-11160868-B2 | Thermoreversible compositions for administration of therapeutic agents | Frequency Therapeutics, Inc. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | Frequency Therapeutics, Inc. | 2021-09-30 | — | — | US | disclosed |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | Frequency Therapeutics, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20200316089-A1 | 1,2-DIHYDRO-3H-PYRAZOL-3-ONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. | 2020-10-08 | — | — | US | disclosed |
| WO-2018053316-A1 | IMPROVED HYBRID TELODENDRIMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-22 | — | — | WO | disclosed |
| US-20170252448-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | Frequency Therapeutics, Inc. | 2017-09-07 | — | — | US | disclosed |
| EP-3035968-A2 | TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME | The Research Foundation for the State University of New York (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015027054-A2 | TELODENDRIMERS AND NANOCARRIERS AND METHODS OF USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2015-02-26 | — | — | WO | disclosed |
| US-5097097-A | Tracers, medical diagnosis | ABBOTT LABORATORIES (US) | 1992-03-17 | — | — | US | disclosed |
| EP-0043285-B2 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4593089-A | Determining aminoglycosides | ABBOTT LABORATORIES (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0043285-B1 | METHOD FOR DETERMINATION OF VALPROIC ACID AND REAGENTS THEREIN | Dainippon Pharmaceutical Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
| US-4420568-A | DETERMINING LIGANDS IN SAMPLE | ABBOTT LABORATORIES (US) | 1983-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160868-B2 | Thermoreversible compositions for administration of therapeutic agents | MKI67, MCL1, HSPE1 | CHRM1 4879/4885AKR1A1 2463/4885CHRM3 4805/4885 |
| US-20210300948-A1 | 1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS | MCL1, PROX1, MKI67 | CHRM1 4722/4885AKR1A1 2773/4885CHRM3 4821/4885 |
| US-20220096639-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | MKI67, MCL1, HSPE1 | CHRM1 4879/4885AKR1A1 2463/4885CHRM3 4805/4885 |
| US-20200316089-A1 | 1,2-DIHYDRO-3H-PYRAZOL-3-ONE COMPOUNDS AND METHODS OF USING SAME | DCX, MCL1, MKI67 | CHRM1 4660/4885AKR1A1 3153/4885CHRM3 4561/4885 |
| US-20170252448-A1 | THERMOREVERSIBLE COMPOSITIONS FOR ADMINISTRATION OF THERAPEUTIC AGENTS | MKI67, MCL1, HSPE1 | CHRM1 4879/4885AKR1A1 2463/4885CHRM3 4805/4885 |
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | DCX, NES, MCL1 | CHRM1 3860/4885AKR1A1 1868/4885CHRM3 4246/4885 |
| US-11066419-B2 | 1H-pyrrole-2,5-dione compounds and methods of using same | MKI67, PROX1, DCX | CHRM1 4667/4885AKR1A1 2276/4885CHRM3 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.