Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydralazine SCHEMBL1374523 | 0.77 | ALDH1A1 (0.75) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL29794531 | 0.77 | ALDH1A1 (0.75) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL2129435 | 0.76 | ALDH1A1 (0.72) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL28451578 | 0.76 | ALDH1A1 (0.72) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL29950602 | 0.76 | ALDH1A1 (0.72) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL149629 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL29484435 | 0.73 | ALDH1A1 (1.00) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| Dihydralazine SCHEMBL3462832 | 0.69 | ALDH1A1 (0.90) | ALDH1A1MAOAPTGS1MAPTTDP1 | |
| SCHEMBL8536092 | 0.69 | KDM4E (0.44) | KDM4ECYP3A4SMN1; SMN2NPC1CYP1A2 | |
| SCHEMBL19358618 | 0.67 | MAPT (0.75) | ALDH1A1MAOAPTGS1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274467-B1 | HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM | GEHO, W., Blair (US) | 1992-05-20 | — | — | EP | claimed |