Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288621 | 0.83 | NOTUM (0.36) | NOTUMTSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5179619 | 0.80 | NOTUM (0.47) | NOTUMTSHRALDH1A1CYP3A4 | |
| SCHEMBL7871395 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL27631667 | 0.77 | NOTUM (0.59) | NOTUM | |
| SCHEMBL9747729 | 0.77 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL29620304 | 0.75 | KIF11 (0.36) | NOTUMTSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6313808 | 0.75 | KIF11 (0.36) | NOTUMTSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL12804493 | 0.74 | TMPRSS4 (0.36) | NOTUMTSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL31066559 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4ALOX15SMN1; SMN2 | |
| SCHEMBL3287160 | 0.74 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082971-A | TRIFLUOROMETHYLAMINOBENZENES CONTAINING FLUORINE AND/OR CHLORINE AND THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | claimed |
| US-5082971-A | TRIFLUOROMETHYLAMINOBENZENES CONTAINING FLUORINE AND/OR CHLORINE AND THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4963181-A | Fungicidal 3-cyano-4-phenyl-pyrrole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-16 | — | — | US | disclosed |
| US-4952601-A | Fungicidal 3-cyano-4-phenyl-pyrrole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
| EP-0339422-A1 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-11-02 | — | — | EP | disclosed |
| EP-0315869-A2 | 3-Cyano-4-(2,4-difluor-3-phenyl)-pyrrole | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0315863-A2 | Trifluoromethylamino benzenes containing fluorine, and their preparation | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |