Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748851 | 0.84 | HPGD (0.55) | SMN1; SMN2LMNARAB9ANPC1MEN1 | |
| SCHEMBL9749420 | 0.77 | ALDH1A1 (0.64) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL10872912 | 0.73 | NPC1 (0.62) | SMN1; SMN2HTTLMNARAB9ANPC1 | |
| SCHEMBL21119057 | 0.70 | ACMSD (0.55) | SMN1; SMN2HTTLMNACSNK2A2CSNK2B | |
| SCHEMBL30989232 | 0.70 | ACMSD (0.55) | SMN1; SMN2HTTLMNACSNK2A2CSNK2B | |
| SCHEMBL6347118 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTRAB9AACMSDNPC1 | |
| SCHEMBL12581571 | 0.70 | APEX1 (0.65) | SMN1; SMN2HTTLMNARAB9AACMSD | |
| SCHEMBL46936 | 0.70 | FOLH1 (0.59) | SMN1; SMN2HTTRAB9AARMRGPRX4 | |
| SCHEMBL315037 | 0.70 | SMN1; SMN2 (0.68) | SMN1; SMN2HTTLMNACSNK2A2CSNK2B | |
| SCHEMBL39630 | 0.70 | FOLH1 (0.63) | SMN1; SMN2HTTRAB9AKMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |