Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10872912 | 0.85 | NPC1 (0.62) | HPGDLMNAFFAR1KMT2AMEN1 | |
| SCHEMBL9748422 | 0.84 | SMN1; SMN2 (0.60) | HPGDLMNAKMT2AMEN1KDM4E | |
| SCHEMBL9749420 | 0.76 | ALDH1A1 (0.64) | HPGDLMNAFFAR1KMT2AMEN1 | |
| SCHEMBL11181823 | 0.74 | LMNA (0.74) | HPGDLMNAFFAR1KMT2AMEN1 | |
| SCHEMBL10690460 | 0.72 | LMNA (0.54) | HPGDLMNAFFAR1KMT2AGFER | |
| SCHEMBL11299725 | 0.71 | HPGD (0.64) | HPGDLMNAFFAR1KMT2AGFER | |
| SCHEMBL11188489 | 0.71 | HPGD (0.60) | HPGDLMNAFFAR1KMT2AGFER | |
| SCHEMBL2733568 | 0.70 | MAPT (0.61) | HPGDLMNAKMT2AGFERMEN1 | |
| SCHEMBL9748936 | 0.70 | APEX1 (0.51) | HPGDKDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9479429 | 0.69 | LMNA (0.74) | HPGDLMNAFFAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |