Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852320 | 0.84 | MAOB (0.63) | MAOBMCL1PTGESGAAMAPT | |
| SCHEMBL343794 | 0.84 | MCL1 (0.78) | MAOBMCL1PTGESMAOA | |
| SCHEMBL14261446 | 0.83 | MAOB (0.55) | MAOBMCL1ABCB1PTGESMAOA | |
| SCHEMBL9748707 | 0.82 | CYP19A1 (0.66) | ABCB1CYP19A1GAAMAPTSLC5A1 | |
| SCHEMBL560607 | 0.81 | MAOB (0.81) | MAOBMCL1PTGESMAPTMAOA | |
| SCHEMBL7947250 | 0.80 | TDP1 (0.65) | MAOBMCL1PTGESMAOA | |
| SCHEMBL9877037 | 0.80 | MAOB (0.60) | MAOBMCL1PTGESMAOA | |
| SCHEMBL710202 | 0.79 | MAOB (0.63) | MAOBMCL1PTGESMAPTMAOA | |
| SCHEMBL29717105 | 0.79 | MAOB (0.63) | MAOBMCL1PTGESMAPTMAOA | |
| SCHEMBL1557011 | 0.78 | FFAR1 (0.71) | FFAR1FFAR4MAOBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120874-A | Process for the preparation of 5-hydroxydiprafenone and its acid addition salts | HELOPHARM W. PETRIK GMBH & CO. KG (DE) | 1992-06-09 | — | — | US | claimed |
| EP-0283540-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYDIPRAPHENONE AND ITS SALTS WITH ACIDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-09-18 | — | — | EP | claimed |
| EP-0283540-A1 | Process for the preparation of 5-hydroxydipraphenone and its salts with acids | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-09-28 | — | — | EP | claimed |
| US-5120874-A | Process for the preparation of 5-hydroxydiprafenone and its acid addition salts | HELOPHARM W. PETRIK GMBH & CO. KG (DE) | 1992-06-09 | — | — | US | disclosed |
| EP-0283540-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYDIPRAPHENONE AND ITS SALTS WITH ACIDS | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0283540-A1 | Process for the preparation of 5-hydroxydipraphenone and its salts with acids | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1988-09-28 | — | — | EP | disclosed |