SCHEMBL9748502

SCHEMBL9748502

Cc1cc(C)cc(CC(C)(C)C=O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
MAPT P10636 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
TSHR P16473 2/20 0.58
CYP3A4 P08684 2/20 0.58
MEN1 O00255 1/20 0.58
USP2 O75604 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
MAPK1 P28482 1/20 0.58
BLM P54132 1/20 0.58
KMT2A Q03164 1/20 0.58
ATM Q13315 1/20 0.58
HIF1A Q16665 1/20 0.58
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
IDH1 O75874 1/20 0.32
ERN1 O75460 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697989 0.82 MEN1 (0.46) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL29845719 0.82 MEN1 (0.46) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL1216706 0.80 TSHR (0.47) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL8955160 0.79 CYP1A2 (0.66) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL27928374 0.78 MEN1 (0.42) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL9749907 0.77 CYP3A4 (0.37) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL30834937 0.75 ALDH1A1 (0.47) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL29143186 0.75 ALDH1A1 (0.47) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL2372640 0.74 ALDH1A1 (1.00) ALDH1A1MAPTNPSR1TSHRCYP3A4
SCHEMBL11347606 0.73 ALDH1A1 (0.81) ALDH1A1MAPTNPSR1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101671240-B Method for preparing 2,2-dimethyl-3-hydrocinnnamic aldehyde and derivative thereof SHANGHAI INST TECHNOLOGY 2013-06-19 CN disclosed
EP-0217159-B1 ALDEHYDES, ACETALS, ALCOHOLS AND ETHERS WITH 3-METHYL OR 3,5-DIMETHYLBENZYL GROUPS, THEIR PREPARATION AND THEIR USE AS FRAGRANCE COMPOUNDS Consortium für elektrochemische Industrie GmbH (DE) 1992-01-02 EP disclosed
US-4710316-A Aldehydes, acetals, alcohols and ethers having 3-methyl- or 3,5-dimethyl-benzyl groups, their manufacture and perfume materials containing same CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1987-12-01 US disclosed
EP-0217159-A2 Aldehydes, acetals, alcohols and ethers with 3-methyl or 3,5-dimethylbenzyl groups, their preparation and their use as fragrance compounds Consortium für elektrochemische Industrie GmbH (DE) 1987-04-08 EP disclosed