Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.58 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347606 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL11268104 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL11272369 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL11266501 | 0.81 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL8955160 | 0.79 | CYP1A2 (0.66) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL4729051 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL3238817 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL16772307 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL11272441 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AMAPTTSHRMAPK1 | |
| SCHEMBL22356835 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KMT2AMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11883459-B2 | Thiol isomerases inhibitors for the treatment and prevention of food allergies, allergic diseases, and inflammatory diseases | WESTERN NEW ENGLAND UNIVERSITY (US) | 2024-01-30 | — | — | US | claimed |
| WO-2011113904-A1 | MEDICAMENTS FOR THE PREVENTION AND TREATMENT OF A DISEASE ASSOCIATED WITH RETINAL GANGLION CELL DEGENERATION | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-09-22 | — | — | WO | claimed |
| EP-0027426-B1 | A PROCESS FOR PREPARING 3-(3,5-DI-TERT. ALKYL-4-HYDROXYPHENYL)-2,2-DI SUBSTITUTED PRIONALDEHYDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1983-04-06 | — | — | EP | claimed |
| US-4284823-A | Process for preparing 3-(3,5-di-tert.alkyl-4-hydroxy-phenyl)-2,2-di-substituted propionaldehydes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-08-18 | — | — | US | claimed |
| EP-0027426-A1 | A process for preparing 3-(3,5-di-tert. alkyl-4-hydroxyphenyl)-2,2-di substituted prionaldehydes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-04-22 | — | — | EP | claimed |
| US-20250352509-A1 | METHOD FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS USING QUERCETIN-CONTAINING COMPOSITIONS | Quercis Pharma AG (CH) | 2025-11-20 | — | — | US | disclosed |
| US-20250275936-A1 | METHOD FOR TREATING CANCERS AND NEUROLOGICAL DISEASES USING QUERCETIN-CONTAINING COMPOSITIONS | Quercis Pharma AG (CH) | 2025-09-04 | — | — | US | disclosed |
| US-12403122-B2 | Method for treating amyotrophic lateral sclerosis using quercetin-containing compositions | Quercis Pharma AG (CH) | 2025-09-02 | — | — | US | disclosed |
| EP-3585809-B1 | ZAFIRLUKAST FOR USE IN TREATING THROMBOSIS | WESTERN NEW ENGLAND UNIV (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-117999074-A | Composition containing quercetin for treating amyotrophic lateral sclerosis | 奎尔塞斯制药股份公司 | 2024-05-07 | — | — | CN | disclosed |
| US-20240108600-A1 | THIOL ISOMERASES INHIBITORS AND USE THEREOF | WESTERN NEW ENGLAND UNIVERSITY | 2024-04-04 | — | — | US | disclosed |
| EP-4340828-A1 | QUERCETIN-CONTAINING COMPOSITIONS FOR USE IN TREATING AMYOTROPHIC LATERAL SCLEROSIS | Quercis Pharma AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| US-4284823-A | Process for preparing 3-(3,5-di-tert.alkyl-4-hydroxy-phenyl)-2,2-di-substituted propionaldehydes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0027426-A1 | A process for preparing 3-(3,5-di-tert. alkyl-4-hydroxyphenyl)-2,2-di substituted prionaldehydes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-04-22 | — | — | EP | disclosed |
| US-4243816-A | PLASTIC STABILIZERS; DISCOLORATION INHIBITION | CIBA-GEIGY CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4177213-A | WITH N,N-DIALKYLDITHIOCARBAMIC ACID P-HYDROXY BENZYL ESTERS | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |
| US-4134879-A | AGING RESISTANCE, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4132702-A | Phenol esters and amides and polymers stabilized therewith | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4091225-A | ALKYLATION, REDUCTION, TRANSESTERIFICATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4013619-A | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108600-A1 | THIOL ISOMERASES INHIBITORS AND USE THEREOF | PDIA5, PDIA4, PDIA6 | ALDH1A1 2477/4885KMT2A 4735/4885MAPT 1738/4885 |
| US-11883459-B2 | Thiol isomerases inhibitors for the treatment and prevention of food allergies, allergic diseases, and inflammatory diseases | SERPINB1, PPIE, TST | ALDH1A1 330/4885KMT2A 3516/4885MAPT 3844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.