Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398255 | 0.82 | AOC3 (0.50) | RIPK1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11206337 | 0.79 | KDM4E (0.45) | RIPK1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11583111 | 0.79 | HRH1 (0.56) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19723310 | 0.77 | AOC3 (0.49) | RIPK1KDM4EAOC3LMNAALDH1A1 | |
| SCHEMBL95323 | 0.76 | RIPK1 (0.55) | RIPK1KDM4EAOC3LMNAL3MBTL1 | |
| SCHEMBL7484922 | 0.76 | RIPK1 (0.55) | RIPK1KDM4EAOC3LMNAL3MBTL1 | |
| SCHEMBL11237204 | 0.75 | RIPK1 (0.46) | RIPK1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14356718 | 0.75 | RIPK1 (0.46) | RIPK1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2745411 | 0.74 | RIPK1 (0.53) | RIPK1KDM4EAOC3LMNAALDH1A1 | |
| SCHEMBL10672887 | 0.72 | AOC3 (0.62) | RIPK1KDM4EAOC3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166437-A | Process for the preparation of fluoxetine | ORION-YHTYMA OY (FI) | 1992-11-24 | — | — | US | disclosed |